Is there a vaccine for Japanese Encephalitis?

  • Central Research Institute, Kasuali, has developed Japanese encephalitis vaccine indigenously.
  • It is a mouse brain killed vaccine and 3 doses are required to produce primary immunization. Two doses are administered sub-cutaneously within a gap of 7-14 days followed by third dose any time after one month and before one year of the second dose. A booster is required after 3 years.
  • Mouse brain technology has limitations in huge production beyond a few million.
  • Tissue culture vaccines with feasibility of mass production are under various phases of development, standardization and/or commercialization.