KALA-AZAR
 
What is Kala-azar?

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  • Kala-azar is a slow progressing indigenous disease caused by a protozoan parasite of genus Leishmania
  • In India Leishmania donovani is the only parasite causing this disease
  • The parasite primarily infects reticuloendothelial system and may be found in abundance in bone marrow, spleen and liver.
  • Post Kala-azar Dermal Leishmaniasis (PKDL) is a condition when Leishmania donovani invades skin cells, resides and develops there and manifests as dermal leisions. Some of the kala-azar cases manifests PKDL after a few years of treatment. Recently it is believed that PKDL may appear without passing through visceral stage. However, adequate data is yet to be generated on course of PKDL manifestation